By Stanley T. Crooke,Archie W. Prestayko
Part I is a normal evaluate of anti-cancer medicines as regards their motion mechanisms, pharmacokinetics, pharmacology, identified toxicities, and scientific software. those medicines contain alkylating brokers akin to mitomycin C and nitrosoureas; plant alkaloids equivalent to maytansine; antibiotics comparable to anthracyclines; platinum-containing complexes; antimetabolites; and hormones. half II examines the molecular pharmacology of a few significant drug periods, particularly, bleomycin and anthracycline. The textual content additionally discusses the chemistry, mechanism, and any structure-activity relationships present in those drug sessions. half III discusses intimately the medical pharmacology of a few antitumor medicines, for instance, cisplatin and nitrosoureas. The textual content comprises the medical purposes, biochemistry, metabolism, and using mathematical types in studying or describing ensuing info.
The publication is useful for pharmacologists, molecular biologists, and scientists occupied with cancer-research.
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Extra info for Antineoplastic Agents: Antineoplastic Agents v. 3
Antineoplastic Agents: Antineoplastic Agents v. 3 by Stanley T. Crooke,Archie W. Prestayko